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Skin Test Responses as Predictors of Tuberculous Infection and of Progression in HIV-infected Persons

Richard S. Kornbluth, MD, PhD
[+] Article, Author, and Disclosure Information

University of California, San Diego, CA 92093. Requests for Reprints: J. Allen McCutchan, MD, UCSD Treatment Center, 2760 Fifth Avenue, Suite 300, San Diego, CA 92103-6329. Grant Support: In part by NIH grants AI25316 and HL43523 (to RSK) and The California University-wide AIDS Research Program through the California Collaborative Treatment Group (to JAM).

Copyright 2004 by the American College of Physicians

Ann Intern Med. 1993;119(3):241-243. doi:10.7326/0003-4819-119-3-199308010-00011
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Three articles in this issue of Annals [13] address some difficult issues about delayed-type hypersensitivity (DTH) skin testing in patients with human immunodeficiency virus (HIV) infection. These issues include how to interpret reactions to purified protein derivative (PPD or tuberculin), how CD4 cell counts and reactions to other skin tests affect this interpretation, and whether skin test results are independent predictors of disease progression. Thus, these and other studies are providing a clearer picture that will help guide clinical decisions.

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