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Aspirin in the Prevention of Colorectal Cancer

Harinder S. Garewal, MD, PhD
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Veterans Affairs Medical Center, Tucson, AZ 85723 Requests for Reprints: Harinder S. Garewal, MD, PhD, Professor of Medicine, Assistant Director, Cancer Prevention and Control, Section of Hematology-Oncology (111D), Veterans Affairs Medical Center, 3601 South 6th Avenue, Tucson, AZ 85723. Grant Support: In part by the Department of Veterans Affairs Cooperative Studies Program (study #380) and the National Cancer Institute grant PO1 CA41108-08.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1994;121(4):303-304. doi:10.7326/0003-4819-121-4-199408150-00013
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In 1993, there were approximately 152 000 new cases of and 57 000 deaths from colorectal cancer, making this disease one of the most prevalent and lethal malignancies in the United States [1]. A person older than 50 years has about a 5% chance of developing colorectal cancer and a 2.5% chance of dying of the disease. Although slightly more common in men, it is a major health risk for both sexes. Early lesions have an excellent cure rate, but advanced, metastatic disease remains incurable. Thus, the most promising approaches to decreasing the morbidity and mortality from colorectal cancer lie in early detection and prevention.

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