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Call for Comments on a Proposal To Improve Reporting of Clinical Trials in the Biomedical Literature

Working Group on Recommendations for Reporting of Clinical Trials in the Biomedical Literature.
[+] Article and Author Information

For members of the Working Group, see the Appendix. Requests for Reprints: Susan Eastwood, ELS(D), Department of Neurological Surgery, Box 0926, c/o The Editorial Office, 1360 Ninth Avenue, Suite 210, San Francisco, CA 94122.


Copyright ©2004 by the American College of Physicians


Ann Intern Med. 1994;121(11):894-895. doi:10.7326/0003-4819-121-11-199412010-00015
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Published guidelines for reporting clinical-research data range from the succinct paragraph on statistics in the “Uniform Requirements for Manuscripts Submitted to Biomedical Journals” [1] to articles of differing detail [27] and books written for the clinical researcher [810]. Despite such excellent resources in the biomedical literature, neither investigators reporting clinical trials nor journal editors selecting reports of trials for publication follow those guidelines consistently. For this reason, a working group of medical journal editors, biostatisticians, researchers, and editors from biomedical institutions met to consider how reporting of clinical-trials data might be made more consistent and complete. The group proposed that 1) editors of journals publishing reports of clinical trials are the persons best positioned to promote better reporting by investigators submitting papers to their journals, and 2) a readily accessible guide to the most basic methodologic elements required in reports of clinical trials could be helpful to journal editors and peer reviewers in evaluating reports of trials submitted for publication.

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