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Clarithromycin Therapy for Mycobacterium avium Complex Disease in Patients with AIDS: Potential and Problems

Mark Goldberger, MD; and Henry Masur, MD
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Food and Drug Administration; Rockville, MD 20857 National Institutes of Health; Bethesda, MD 20892-1662 Disclaimer: This article represents the views of the authors and does not represent official policy of the National Institutes of Health or the Food and Drug Administration.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1994;121(12):974-976. doi:10.7326/0003-4819-121-12-199412150-00012
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The quality and duration of survival for patients with human immunodeficiency virus (HIV) infection have improved substantially during the past decade. Much of this improvement has been because of better management of opportunistic infections. However, progress with Mycobacterium avium complex, a pathogen that ultimately infects 30% to 50% of patients with the acquired immunodeficiency syndrome (AIDS) in North America, has until recently been disappointing, especially in terms of prophylaxis and therapy.

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