0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

Insulinoma: Cost-effective Care in Patients with a Rare Disease

Lloyd Axelrod, MD
[+] Article and Author Information

Massachusetts General Hospital, Boston, MA 02114 Requests for Reprints: Lloyd Axelrod, MD, Diabetes Unit, Bulfinch 408, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114.


Copyright ©2004 by the American College of Physicians


Ann Intern Med. 1995;123(4):311-312. doi:10.7326/0003-4819-123-4-199508150-00011
Text Size: A A A

An insulinoma is the quintessential example of the elusive but curable endocrine disorder. It is a rare condition, estimated to occur four times per million person-years [1], and has nonspecific neurologic and adrenergic manifestations. It frequently eludes diagnosis for years. The neurologic manifestations, especially those that affect behavior and consciousness, are often frightening and embarrassing to those who have this condition and to those around them. An insulinoma is potentially lethal. Once identified, it is curable by surgery [1]. When an isolated benign insulinoma is removed (and most are benign), the patient has a normal life expectancy [1]. A patient with an insulinoma presents a series of challenges. The physician must recognize that the patient's symptoms are attributable to hypoglycemia, exclude other exogenous and endogenous causes of hypoglycemia, obtain appropriate hormonal studies to establish the diagnosis beyond any doubt, and guide the patient toward appropriate surgical treatment.

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)