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Whither Interferon for Myeloma and Other Hematologic Malignancies?

Raymond Alexanian, MD; and Donna Weber, MD
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University of Texas Houston, TX 77030 Grant Support: In part by the Robert Hompe Myeloma Research Fund. Requests for Reprints: Raymond Alexanian, MD, University of Texas M.D. Anderson Cancer Center, Box 001, 1515 Holcombe Boulevard, Houston, TX 77030. Current Author Addresses: Drs. Alexanian and Weber: University of Texas M.D. Anderson Cancer Center, Box 001, 1515 Holcombe Boulevard, Houston, TX 77030.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1996;124(2):264-265. doi:10.7326/0003-4819-124-2-199601150-00012
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Multiple myeloma is one of the common hematologic malignancies now affecting approximately 12 500 persons in the United States each year. The number of patients with this condition continues to increase as a result of more frequent screening with electrophoresis and more diagnoses among a progressively aging population. Despite intensive study of many treatments, including those supported by stem cell transplantation, overall survival has not improved, and the disease remains incurable [1]. Accordingly, the best available strategy has been to achieve a high frequency of remission that can be sustained for several years, and then to repeatedly control relapsing disease with a series of effective and well-tolerated treatments.

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