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Colonic Bacillary Angiomatosis

Young B. Huh, MD; Suzanne Rose, MD; Robert E. Schoen, MD, MPH; Susan Hunt, MD; David C. Whitcomb, MD, PhD; and Sydney Finkelstein, MD
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From the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Requests for Reprints: Suzanne Rose, MD, University of Pittsburgh Medical Center, Division of Gastroenterology and Hepatology, 200 Lothrop Street, Mezzanine Level, C Wing, Presbyterian University Hospital, Pittsburgh, PA 15213. Current Author Addresses: Drs. Huh, Rose, Schoen, and Whitcomb: University of Pittsburgh Medical Center, Division of Gastroenterology and Hepatology, 200 Lothrop Street, Mezzanine Level, C Wing, Presbyterian University Hospital, Pittsburgh, PA 15213.

Ann Intern Med. 1996;124(8):735-737. doi:10.7326/0003-4819-124-8-199604150-00005
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Bacillary angiomatosis is an infectious disease caused by small, fastidious, gram-negative bacilli known as Bartonella henselae and B. quintana (formerly Rochalimaea henselae and R. quintana) [1]. The infection is characterized by a vascular proliferation of the skin or visceral organs and usually occurs in immunosuppressed patients [2].

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Figure 1.
Colonic bacillary angiomatosis.Top left and Top right.Bottom left.arrowsBottom right.arrows

Endoscopic appearance of several reddish nodules with intervening ulcerations in the rectosigmoid colon. Colonic biopsy specimen. The colonic mucosa has been replaced by an acute inflammatory cell infiltrate with abundant thin-walled fibrovascular vascular channels (Vs) lined by prominent endothelial cells ( ). Hematoxylin and eosin stain; original magnification × 400. Warthin-Starry stain of colonic biopsy specimen. Areas of mucosal destruction contain many Warthin-Starry positive rod-shaped organisms ( ) consistent with a diagnosis of bacillary angiomatosis. Warthin-Starry stain; original magnification × 1000.

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