In December 1994, Annals of Internal Medicine published a paper titled “Call for Comments on a Proposal to Improve Reporting of Clinical Trials in the Biomedical Literature” [1]. The proposal was the undertaking of the Asilomar Working Group on Recommendations for Reporting of Clinical Trials in the Biomedical Literature, which includes the principal editors of four medical journals, four biostatisticians, two biomedical investigators, three academic biomedical editors, and an information scientist, all of whom participate professionally in the planning, performance, reporting, or publishing of clinical trials. This call for comments also appeared in the journals of several professional societies for scientific editors, including the American Medical Writers Association, the Council of Biology Editors, the European Association of Science Editors, and the International Federation of Science Editors. In this call for comments, the Asilomar Working Group stated the following.