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1996–97 Series

John Roberts, MD, Editor

Update in Cardiology

Joseph S. Alpert, MD; and Melvin D. Cheitlin, MD
[+] Article, Author, and Disclosure Information

From Arizona Health Science Center, Tucson, Arizona, and San Francisco General Hospital, San Francisco, California. Current Author Addresses: Dr. Alpert: Arizona Health Science Center, 1501 North Campbell Avenue, Room 6334, Tucson, AZ 85724.

Ann Intern Med. 1996;125(1):40-46. doi:10.7326/0003-4819-125-1-199607010-00007
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Much of the recent research in cardiology has focused on the pathophysiology of coronary artery disease and the clinical implications that result from an understanding of that physiology, especially the implications surrounding the reduction of cholesterol levels. In addition, studies published in the past year have shown good evidence for the effectiveness of afterload reduction in patients with asymptomatic aortic regurgitation and of carefully monitored anticoagulation in patients with atrial fibrillation. Finally, a previously common practice in patients with myocarditis has been shown to have no effect on outcome.

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Figure 1.
Effects of pravastatin therapy on plasma low-density lipoprotein (LDL) cholesterol levels.
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Figure 2.
Kaplan-Meier analysis of the time to a definite nonfatal myocardial infarction or death from coronary heart disease, according to treatment.
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