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Zinc: The Biology and Therapeutics of an Ion

Ananda S. Prasad, MD, PhD
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Wayne State University, School of Medicine, Detroit, MI 48201 Requests for Reprints: Ananda S. Prasad, MD, PhD, Department of Internal Medicine, Wayne State University Health Center, 5C, 4201 St. Antoine, Detroit, MI 48201.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1996;125(2):142-143. doi:10.7326/0003-4819-125-2-199607150-00012
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Although the role of zinc in the growth of microorganisms, plants, and animals was well established many decades ago, its role in humans was first recognized only in 1963 [1]. Our studies from the Middle East showed, for the first time, that zinc deficiency occurs in humans [1]. In 1974, the Food and Nutrition Board of the National Research Council of the National Academy of Sciences [2] made a landmark decision to establish a recommended dietary allowance for zinc as an essential element for humans.



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