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Treatment of Cytomegalovirus Retinitis in Patients with AIDS

Douglas A. Jabs, MD
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Wilmer Eye Institute, Baltimore, MD 21205 Requests for Reprints: Douglas A. Jabs, MD, Wilmer Eye Institute, 550 North Broadway, Suite 700, Baltimore, MD 21205.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1996;125(2):144-145. doi:10.7326/0003-4819-125-2-199607150-00013
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Cytomegalovirus (CMV) is among the most common opportunistic infections in patients with the acquired immunodeficiency syndrome (AIDS) [13]. In the era of prophylaxis for Pneumocystis carinii pneumonia, disease caused by CMV has been reported to affect as many as 45% of patients with AIDS at some time during the course of disease [2]. Although CMV may affect the eyes, gastrointestinal tract, lungs, and central nervous system, CMV retinitis accounts for 85% of all CMV disease in patients with AIDS [3]. Untreated CMV retinitis spreads through the retina and causes total retinal destruction and blindness [45]. Hence, CMV retinitis is a major cause of morbidity in patients with AIDS.

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