The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Moderate Alcohol Consumption and Risk for Angina Pectoris or Myocardial Infarction in U.S. Male Physicians

Carlos A. Camargo Jr., MD; Meir J. Stampfer, MD; Robert J. Glynn, ScD; Francine Grodstein, ScD; J. Michael Gaziano, MD; JoAnn E. Manson, MD; Julie E. Buring, ScD; and Charles H. Hennekens, MD
[+] Article, Author, and Disclosure Information

From the Channing Laboratory, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, and Harvard School of Public Health, Boston, Massachusetts. Acknowledgments: The authors thank Marilyn Chown for her assistance with data analysis. Grant Support: By grants HL-26490, HL-34595, CA-34944, CA-40360, and CA-42182 from the National Institutes of Health. Dr. Camargo is supported by an institutional training grant (HL-07575) from the National Heart, Lung, and Blood Institute. Requests for Reprints: Charles Hennekens, MD, Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, MA 02215-1204. Current Author Addresses: Drs. Camargo, Stampfer, and Grodstein: Channing Laboratory, Brigham and Women's Hospital, 181 Longwood Avenue, boston, MA 02115.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1997;126(5):372-375. doi:10.7326/0003-4819-126-5-199703010-00005
Text Size: A A A

Background: Although previous studies have found that moderate alcohol intake decreases the risk for myocardial infarction, many clinicians question the validity of this finding. Furthermore, the relation of moderate drinking to the risk for other events, such as angina pectoris, is not known.

Objective: To determine whether moderate alcohol intake decreases the risk for angina pectoris or myocardial infarction in apparently healthy men.

Design: Prospective cohort study.

Setting: United States.

Participants: 22 071 apparently healthy male physicians who were 40 to 84 years of age between 1981 and 1984.

Measurements: Responses to annual questionnaires.

Results: Through 1994, 1368 cases of new-onset angina and 690 cases of myocardial infarction had been documented. In multivariate analyses that controlled for several potential confounders, alcohol intake was strongly and inversely associated with the risk for each event (P for trend < 0.001). Compared with men who consumed less than one drink per week, those who consumed one drink per day had relative risks of 0.69 (95% CI, 0.59 to 0.81) for angina and 0.65 (CI, 0.52 to 0.81) for myocardial infarction. These associations were seen when either nondrinkers or occasional drinkers were used as the reference group.

Conclusions: Moderate drinking decreases the risk for angina pectoris and myocardial infarction in apparently healthy men.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $32.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.