0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Hearing Loss in the Sjogren Syndrome

Bruno Tumiati, MD; Patrizia Casoli, MD; and Alfredo Parmeggiani, MD
[+] Article and Author Information

From Ospedale Santa Maria Nuova, Reggio Emilia, Italy. Acknowledgment: The authors thank Mrs. Antonella Berselli for technical assistance. Requests for Reprints: Bruno Tumiati, MD, 2nd Department of Internal Medicine, Ospedale S. Maria Nuova, Viale Risorgimento, 42100 Reggio Emilia, Italy. Current Author Addresses: Drs. Tumiati and Casoli: 2nd Department of Internal Medicine, Ospedale S. Maria Nuova, Viale Risorgimento, 42100 Reggio Emilia, Italy.


Copyright ©2004 by the American College of Physicians


Ann Intern Med. 1997;126(6):450-453. doi:10.7326/0003-4819-126-6-199703150-00005
Text Size: A A A

Background: Ear involvement is not unusual in autoimmune diseases, but few data on this problem in the Sjogren syndrome are available.

Objectives: To determine whether the incidence of hearing loss is increased in patients with the Sjogren syndrome and to determine what factors might be involved in the pathogenesis of Sjogren syndrome-related hearing loss.

Design: Cross-sectional study.

Setting: Secondary referral center in ltaly.

Patients: 30 women with the Sjogren syndrome were evaluated for evidence of audiovestibular disorder. Their results were compared with those of 40 age-matched healthy women.

Measurements: Evaluation techniques included pure tone audiometry thresholds at octave frequencies of 125 Hz to 8000 Hz, tympanometry, and the stapedial reflex test in both ears. The presence of vasculitis, the Raynaud phenomenon, nervous system involvement, and serum anticardiolipin antibodies was recorded.

Results: 14 patients with the Sjogren syndrome (46% [95% CI, 28% to 66%]) had sensorineural hearing loss. Only one control (2.5% [CI, 0.06% to 13%]) had a similar hearing impairment (P < 0.001). Nine of the 14 patients who had the Sjogren syndrome and sensorineural hearing loss (64% [CI, 36% to 87%]) had anticardiolipin antibodies compared with only 3 controls (18% [CI, 4% to 45%]) (P = 0.02).

Conclusion: The high prevalence of hearing loss in the Sjogren syndrome supports the value of doing audiometric studies before excluding cranial nerve involvement in this disease. The correlation of sensorineural hearing loss with anticardiolipin antibodies must be investigated further.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)