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The Changing Clinical Spectrum of Adrenal Insufficiency

Robert M. Carey, MD
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University of Virginia School of Medicine; Charlottesville, VA 22908. Requests for Reprints: Robert M. Carey, MD, Box 395, University of Virginia Health Sciences Center, Charlottesville, VA 22908.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1997;127(12):1103-1105. doi:10.7326/0003-4819-127-12-199712150-00009
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The clinical spectrum of primary adrenal insufficiency has changed substantially over the past decade as a result of the emergence of new disease patterns, improved understanding of clinical presentations, and the impact of molecular genetics. I comment here on five clinical entities that have emerged as new diagnostic or therapeutic challenges in the 1990s.

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