0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Response of Lymphoepithelial Parotid Cysts to Antiretroviral Treatment in HIV-Infected Adults

Donald E. Craven, MD; Robert A. Duncan, MD, MPH; John R. Stram, MD; Carl J. O'Hara, MD; Kathleen A. Steger, RN, MPH; Kristin Jhamb, MD; and Lisa R. Hirschhorn, MD, MPH
[+] Article and Author Information

From the Boston University School of Medicine, Boston Medical Center, and Boston University School of Public Health, Boston, Massachusetts; Lahey Hitchcock Clinic, Burlington, Massachusetts; and Dimock Community Health Center, Roxbury, Massachusetts. Acknowledgments: The authors thank Maria Tetzaguic for assistance in manuscript preparation; Dr. Margaret Sullivan for patient information and manuscript review; and Dr. Sanjay Ram, Colleen LaBelle, RN, Carrie Grodman, RN, and Sharon Irvin, LPN, for patient information. Requests for Reprints: Donald E. Craven, MD, Boston Medical Center, Dowling 3 North, 1 Boston Medical Center Place, Boston, MA 02118. Current Author Addresses: Dr. Craven and Ms. Steger: Boston Medical Center, Dowling 3 North, 1 Boston Medical Center Place, Boston, MA 02118.


Copyright ©2004 by the American College of Physicians


Ann Intern Med. 1998;128(6):455-459. doi:10.7326/0003-4819-128-6-199803150-00006
Text Size: A A A

Background: Surgical resection has been the usual therapy for HIV-infected patients with lymphoepithelial parotid cysts.

Objective: To study antiretroviral therapy for lymphoepithelial parotid cysts.

Design: Case series.

Setting: HIV outpatient clinics.

Patients: HIV-infected patients with lymphoepithelial parotid cysts.

Intervention: Antiretroviral therapy.

Measurements: Change in size of the parotid cyst, CD4 lymphocyte count, and HIV viral load.

Results: Nine HIV-infected adults presented with chronic, large parotid cysts, eight of which were bilateral. In at least seven patients, the cysts were the initial sign of HIV infection. In six patients, the cysts resolved completely with combination antiretroviral therapy. Four of these patients also received prednisone. Three patients who did not comply with antiretroviral therapy had partial responses followed by relapses.

Conclusions: Parotid cysts are an unrecognized sign of early HIV infection. These cysts respond to combination antiretroviral therapy, with or without corticosteroids. Surgical resection should be reserved for patients in whom medical therapy has failed or those who refuse or are poorly compliant with medical therapy.

Figures

Grahic Jump Location
Figure 1.
Lymphoepithelial parotid cyst disease in an HIV-infected patient (patient 2) before (left) and after (right) combination antiretroviral therapy.
Grahic Jump Location

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)