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Incidence of Idiopathic Deep Venous Thrombosis and Secondary Thromboembolism among Ethnic Groups in California

Richard H. White, MD; Hong Zhou, PhD; and Patrick S. Romano, MD, MPH
[+] Article, Author, and Disclosure Information

From University of California, Davis, Sacramento, California Requests for Reprints: Richard H. White, MD, Primary Care Center, Room 3107, 2221 Stockton Boulevard, Sacramento, CA 95817. Current Author Addresses: Drs. White, Zhou, and Romano: Primary Care Center, Room 3107, 2221 Stockton Boulevard, Sacramento, CA 95817.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1998;128(9):737-740. doi:10.7326/0003-4819-128-9-199805010-00006
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Background: Few studies have compared the incidence of deep venous thrombosis among ethnic groups.

Objective: To determine the incidence of deep venous thrombosis among ethnic groups.

Design: Analysis of the linked California Patient Discharge Data Set from 1991 to 1994.

Setting: California.

Patients: 17 991 patients with idiopathic deep venous thrombosis (thrombosis without cancer or hospitalization within preceding 6 months) and 5573 patients with secondary thromboembolism (thromboembolism occurring within 3 months of seven different events).

Measurements: Ethnicity was determined by using race as documented in the data set. For idiopathic deep venous thrombosis, standardized age- and sex-adjusted incidences were calculated. For secondary thromboembolism, proportional hazards modeling was done.

Results: The annual incidence of idiopathic deep venous thrombosis per 1 000 000 persons older than 18 years of age was 230 for white persons, 293 for African Americans (rate ratio, 1.27 [95% CI, 1.07 to 1.51]), 139 for Hispanic persons (rate ratio, 0.60 [CI, 0.54 to 0.67]), and 60 for Asians and Pacific Islanders (rate ratio, 0.26 [CI, 0.22 to 0.30]). Compared with white persons, Asians and Pacific Islanders who developed secondary thromboembolism had a significantly lower relative risk (range, 0.22 to 0.61) for all seven conditions analyzed.

Conclusions: Compared with white persons, Asians and Pacific Islanders have a very low incidence of idiopathic deep venous thrombosis and a very low relative risk for secondary venous thromboembolism.


Grahic Jump Location
Figure 1.
Age- and sex-adjusted relative risk for developing venous thromboembolism within 3 months of a specific medical or surgical event among Asians and Pacific Islanders, African Americans, and Hispanic persons, with white persons as the reference group.

Black bars represent 95% CIs.

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