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Fifty Years of Death Certificates: The Framingham Heart Study

Claude Lenfant, MD; Lawrence Friedman, MD; and Thomas Thom, BA
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National Institutes of Health; Bethesda, MD 20892-2486 Acknowledgments: The authors thank Teri Manolio, MD; Paul Sorlie, PhD; and Sean Coady. Requests for Reprints: Claude Lenfant, MD, National Institutes of Health, Building 31, Room 5A52, 31 Center Drive, Bethesda, MD 20892-2486. Current Author Addresses: Dr. Lenfant: National Institutes of Health, Building 31, Room 5A52, 31 Center Drive, Bethesda, MD 20892-2486.

Copyright ©2004 by the American College of Physicians

Ann Intern Med. 1998;129(12):1066-1067. doi:10.7326/0003-4819-129-12-199812150-00013
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Since the Framingham Heart Study enrolled its first patient in 1948, we have learned much about the epidemiology and pathophysiology of the United States' deadliest malady: coronary heart disease. No single medical research effort has contributed more to our increased awareness and understanding of coronary artery disease than the Framingham Heart Study. The hundreds of scientific reports during the past 50 years that have been based on Framingham data have changed not only the way we think about our patients with coronary disease but also how we actually care for them. In this issue, Lloyd-Jones and colleagues [1] suggest that the Framingham Heart Study has also influenced our consideration of heart disease when determining why an individual patient has died.

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