The Cushing syndrome is a condition that results from too much cortisol in the body. People with the Cushing syndrome accumulate fat in their bodies and faces while their legs and arms remain thin. Other symptoms seen in the Cushing syndrome include abnormal facial hair, menstrual irregularities, high blood pressure, weak muscles, stretch marks on the skin, acne, back pain, bruising, psychological problems, and thinning of the bones. In addition to PPNAD, many other medical conditions can cause the Cushing syndrome. PPNAD is one of the rarest causes of the Cushing syndrome, but it can be associated with a potentially fatal condition known as the Carney complex. People with PPNAD who have the Carney complex develop unusual types of tumors that can be deadly, so you don't want to miss the diagnosis of PPNAD. Unfortunately, the diagnosis is very difficult to make.