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Pharmacologic Treatment of Acute Major Depression and Dysthymia: Clinical Guideline, Part 1

Vincenza Snow, MD; Steven Lascher, DVM, MPH; Christel Mottur-Pilson, PhD, American College of Physicians-American Society of Internal Medicine*.
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For definitions of terms, see Glossary.

For other ACP-ASIM Clinical Practice Guidelines, see http://www.acponline.org/sci-policy/guidelines.

This paper, written by Vincenza Snow, MD, Steven Lascher, DVM, MPH, and Christel Mottur-Pilson, PhD, was developed by the Clinical Efficacy Assessment Subcommittee: David C. Dale, MD, Chair; William E. Golden, MD; Robert D. McCartney, MD; Keith W. Michl, MD; Stephen G. Pauker, MD; Sean R. Tunis, MD; Kevin B. Weiss, MD; Preston L. Winters, MD; and John J. Whyte, MD. Approved by the Board of Regents on 17 July 1999.

Disclaimer: The authors of this article are responsible for its content, including any clinical or treatment recommendations. No statement in this article should be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.

Requests for Single Reprints: Customer Service, American College of Physicians-American Society of Internal Medicine, 190 N. Independence Mall West, Philadelphia, PA 19106.

Requests To Purchase Bulk Reprints (minimum, 100 copies): the Reprints Coordinator; phone, 215-351-2657; e-mail, reprints@mail.acponline.org.

Current Author Addresses: Drs. Snow, Lascher, and Mottur-Pilson: Scientific Policy Department, Education Division, American College of Physicians-American Society of Internal Medicine, 190 N. Independence Mall West, Philadelphia, PA 19106.

Ann Intern Med. 2000;132(9):738-742. doi:10.7326/0003-4819-132-9-200005020-00010
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The numbers in square brackets are cross-references to the numbered sections in the accompanying background paper, “A Systematic Review of Newer Pharmacotherapies for Depression in Adults: Evidence Report Summary,” which is part 2 of this guideline (see pages743-756).

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Adverse effects of selective serotonin reuptake inhibitors (striped bars) and tricyclic antidepressants (white bars).
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