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Physical Activity and Risk for Cardiovascular Events in Diabetic Women

Frank B. Hu, MD; Meir J. Stampfer, MD; Caren Solomon, MD; Simin Liu, MD; Graham A. Colditz, MD; Frank E. Speizer, MD; Walter C. Willett, MD; and JoAnn E. Manson, MD
[+] Article and Author Information

From Harvard School of Public Health, Harvard Medical School, and Brigham and Women's Hospital, Boston, Massachusetts.


Acknowledgments: The authors thank the participants in the Nurses' Health Study for their continuing outstanding level of cooperation and Al Wing, Gary Chase, Karen Corsano, Lisa Dunn, Barbara Egan, Lori Ward, Erin Boyd, and Jill Arnold for their unfailing help.

Grant Support: By the National Institutes of Health (DK 36798 and CA40356). Dr. Hu's work is supported by an American Diabetes Association Research Award. Dr. Caren Solomon is supported by an American Heart Association Clinical Scientist Award.

Requests for Single Reprints: Frank B. Hu, MD, Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115; e-mail, Frank.hu@channing.harvard.edu.

Current Author Addresses: Drs. Hu and Willett: Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115.

Drs. Stampfer, Colditz, and Speizer: Channing Laboratory, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115.

Dr. Solomon: Division of General Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.

Drs. Liu and Manson: Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, MA 02215.

Author Contributions: Conception and design: F.B. Hu, M.J. Stampfer, G.A. Colditz, F.E. Speizer, W.C. Willett, J.E. Manson.

Analysis and interpretation of the data: F.B. Hu, M.J. Stampfer, C. Solomon, S. Liu, G.A. Colditz, W.C. Willett, J.E. Manson.

Drafting of the article: F.B. Hu.

Critical revision of the article for important intellectual content: F.B. Hu, M.J. Stampfer, C. Solomon, S. Liu, G.A. Colditz, F.E. Speizer, W.C. Willett, J.E. Manson.

Final approval of the article: F.B. Hu, C. Solomon, S. Liu, G.A. Colditz, F.E. Speizer, W.C. Willett, J.E. Manson.

Statistical expertise: F.B. Hu, S. Liu, G.A. Colditz, W.C. Willett.

Obtaining of funding: F.B. Hu, F.E. Speizer, W.C. Willett, J.E. Manson.

Administrative, technical, or logistic support: F.B. Hu, G.A. Colditz, F.E. Speizer, J.E. Manson.

Collection and assembly of data: F.B. Hu, G.A. Colditz, W.C. Willett, J.E. Manson.


Ann Intern Med. 2001;134(2):96-105. doi:10.7326/0003-4819-134-2-200101160-00009
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Cardiovascular disease is the leading cause of death in persons with diabetes mellitus. This disorder affects approximately 16 million Americans, at least 15 million of whom have type 2 diabetes mellitus (1). Among diabetic persons, coronary heart disease causes more than 50% of all deaths and stroke causes an additional 15% (2). Diabetic women are at particularly high risk for cardiovascular disease, and diabetes eliminates the usual female advantage for death from coronary disease.

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Summary for Patients

Physical Activity and the Risk for Heart Disease and Stroke in Women with Diabetes

The summary below is from the full report titled “Physical Activity and Risk for Cardiovascular Events in Diabetic Women.” It is in the 16 January 2001 issue of Annals of Internal Medicine (volume 134, pages 96-105). The authors are FB Hu, MJ Stampfer, C Solomon, S Liu, GA Colditz, FE Speizer, WC Willett, and JE Manson.

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