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Cardiovascular Disease and Mortality in Older Adults with Small Abdominal Aortic Aneurysms Detected by Ultrasonography: The Cardiovascular Health Study

Anne B. Newman, MD, MPH; Alice M. Arnold, PhD; Gregory L. Burke, MD; Daniel H. O'Leary, MD; and Teri A. Manolio, MD, MS
[+] Article and Author Information

From University of Pittsburgh, Pittsburgh, Pennsylvania; University of Washington, Seattle, Washington; Wake Forest University, Winston-Salem, North Carolina; Tufts–New England Medical Center, Boston, Massachusetts; and National Heart, Lung, and Blood Institute, Bethesda, Maryland.


Requests for Single Reprints: Anne B. Newman, MD, MPH, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, 3520 Fifth Avenue, Suite 300, Pittsburgh, PA 15213; e-mail, anewman+@pitt.edu.

Current Author Addresses: Dr. Newman: Division of Geriatric Medicine, University of Pittsburgh School of Medicine, 3520 Fifth Avenue, Suite 300, Pittsburgh, PA 15213.

Dr. Arnold: Cardiovascular Health Study, University of Washington, 1501 Fourth Avenue, Suite 2105, Seattle, WA 98101.

Dr. Burke: Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27153.

Dr. O'Leary: Tufts–New England Medical Center, 750 Washington Street, Boston, MA 02111.

Dr. Manolio: National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, MSC 7934, Bethesda, MD 20892-7934.

Author Contributions: Conception and design: A.B. Newman, G.L. Burke, D.H. O'Leary, T.A. Manolio.

Analysis and interpretation of the data: A.B. Newman, A.M. Arnold, G.L. Burke, D.H. O'Leary, T.A. Manolio.

Drafting of the article: A.B. Newman, A.M. Arnold, D.H. O'Leary.

Critical revision of the article for important intellectual content: A.B. Newman, G.L. Burke, D.H. O'Leary, T.A. Manolio.

Final approval of the article: A.B. Newman, A.M. Arnold, G.L. Burke, D.H. O'Leary, T.A. Manolio.

Provision of study materials or patients: A.B. Newman, G.L. Burke, D.H. O'Leary.

Statistical expertise: A.B. Newman, A.M. Arnold.

Obtaining of funding: A.B. Newman, G.L. Burke, D.H. O'Leary, T.A. Manolio.

Administrative, technical, or logistic support: D.H. O'Leary, T.A. Manolio.

Collection and assembly of data: D.H. O'Leary.


Ann Intern Med. 2001;134(3):182-190. doi:10.7326/0003-4819-134-3-200102060-00008
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Rupture of abdominal aortic aneurysm remains an important cause of death in older adults, although screening and monitoring are easily done by using abdominal ultrasonography (12). Determining the timing of surgery is complex because these persons are already at increased risk for cardiovascular complications of surgery (3) and have a higher prevalence of cardiovascular risk factors (48). However, few data are available on the natural history and relative risk for other interim cardiovascular events and mortality.

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Figure.
Survival according to abdominal aortic aneurysm (AAA) classification in 1953 men (top) and 2781 women (bottom) in the Cardiovascular Health Study.
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Summary for Patients

Cardiovascular Disease and Death in Older Adults with Small Aneurysm in the Abdominal Aorta

The summary below is from the full report titled “Cardiovascular Disease and Mortality in Older Adults with Small Abdominal Aortic Aneurysms Detected by Ultrasonography: The Cardiovascular Health Study.” It is in the 6 February 2001 issue of Annals of Internal Medicine (volume 134, pages 182-190). The authors are AB Newman, AM Arnold, GL Burke, DH O'Leary, and TA Manolio.

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