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Increased Mortality among Middle-Aged Women after Myocardial Infarction: Searching for Mechanisms and Solutions

John Z. Ayanian, MD, MPP
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Dr. Ayanian: Harvard Medical School; Boston, MA 02115


Grant Support: By the Agency for Healthcare Research and Quality (R01 HS08071 and R01 HS09718). Dr. Ayanian is an Associate of the John D. and Catherine T. MacArthur Foundation Research Network on Successful Midlife Development.

Requests for Single Reprints: John Z. Ayanian, MD, MPP, Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115; e-mail, ayanian@hcp.med.harvard.edu.


Ann Intern Med. 2001;134(3):239-241. doi:10.7326/0003-4819-134-3-200102060-00015
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Public and professional recognition of the prevalence and clinical impact of coronary heart disease in women has risen over the past decade, fueled in part by studies showing disparities in the use of cardiac procedures between women and men (14). Reacting to the previously established view of coronary heart disease as primarily a male malady (5), researchers and clinicians have increased their attention to the mechanisms, treatment, and consequences of this condition in women. Some hospitals have developed new clinical programs specifically for women with heart disease. Recent evidence has suggested that sex disparities in treatment of myocardial infarction have diminished, at least among elderly patients (67).

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