Ibopamine is a drug that was used in Europe to treat heart failure, a condition in which the heart cannot pump blood normally. In 1995, a study showed that ibopamine increased death rates in patients who had moderate to severe heart failure. In September 1995, doctors and pharmacists in the Netherlands were officially notified that ibopamine should be used only in patients with mild heart failure. Moreover, the official recommendations for when to use ibopamine were changed according to whether patients had mild or severe heart failure. Whether the change in recommendations resulted in fewer deaths related to ibopamine was not known.