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The Kidney in Cardiovascular Disease

Bertram L. Kasiske, MD
[+] Article, Author, and Disclosure Information

Dr. Kasiske: Hennepin County Medical Center; Minneapolis, MN 55415

Acknowledgment: The author thanks Richard Grimm, MD, for helpful suggestions.

Requests for Single Reprints: Bertram L. Kasiske, MD, Department of Medicine, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN 55415; e-mail: kasis001@umn.edu.

Ann Intern Med. 2001;134(8):707-709. doi:10.7326/0003-4819-134-8-200104170-00014
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The past quarter-century has seen remarkable advances in the prevention and treatment of cardiovascular disease. Observational studies have effectively identified modifiable risk factors, such as hypertension and hyperlipidemia. Well-designed randomized, controlled trials have unequivocally shown that treatment of these and other risk factors reduces cardiovascular disease and all-cause mortality. More recent clinical trials are now examining treatment in special populations and are investigating whether some agents may have unique “renoprotective” or “cardioprotective” effects that go beyond targeted reductions in known risk factors.

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