The Goodpasture syndrome (also known as anti–glomerular basement membrane, or anti-GBM, disease) causes kidney failure and, sometimes, bleeding in the lungs. It has been thought that patients who develop severe kidney failure from the Goodpasture syndrome do not usually recover their kidney function, but few large, long-term studies of this condition have been done. The Goodpasture syndrome is probably due to an autoimmune process. This means that the immune system, which should attack only foreign substances such as bacteria, attacks a person's own body tissues. Treatments for the Goodpasture syndrome include plasma exchange, which filters the blood to remove immune substances, and drugs that suppress the immune system, such as prednisone and cyclophosphamide.