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Treatment of Refractory Erdheim–Chester Disease with Double Autologous Hematopoietic Stem-Cell Transplantation

Nicolas Boissel, MD; Bertrand Wechsler, MD; and Véronique Leblond, MD
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Groupe Hospitalier Pitié-Salpêtrière; 75013 Paris, France (Boissel, Wechsler, Leblond)


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Ann Intern Med. 2001;135(9):844-845. doi:10.7326/0003-4819-135-9-200111060-00027
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Figures

Grahic Jump Location
Figure.
An 18-year-old man with Erdheim–Chester disease.

A. Before treatment. B. After treatment. C. Cranial T2-weighted axial magnetic resonance imaging before tandem autologous peripheral stem-cell transplantation. A facial hypointense mass can be seen invading both orbits (the nasal fossae and the sphenoid sinus), exerting a huge mass effect on both ocular globes, which are pushed upward and are therefore not visible. D. Cranial T2-weighted axial magnetic resonance imaging after tandem autologous peripheral blood stem-cell transplantation. Regression of the tumor after treatment can been seen (same slice level as panel C), with disappearance of the hypointense lesion. Hyperintense mucus retention cysts are visible at the level of ethmoid cells.

Grahic Jump Location

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