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Update in Infectious Diseases

Gerald L. Mandell, MD
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From University of Virginia Health Sciences Center, Charlottesville, Virginia.

Requests for Single Reprints: Gerald L. Mandell, MD, Division of Infectious Diseases, University of Virginia Health Sciences Center, Building MR4, Room 2112, Charlottesville, VA 22908.

Ann Intern Med. 2001;135(10):897-905. doi:10.7326/0003-4819-135-10-200111200-00010
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In this Update, I cover developments in the management of hepatitis C, which is most often first encountered by general internists and treated by hepatologists rather than infectious disease consultants. I also describe several recent reports on the current state of antibiotic resistance and promising new approaches to this expanding problem. Following that discussion are sections on prevalent infections, including the common cold, sinusitis, and influenza, and on less common infectious disorders that nevertheless pose an increasing threat; for example, those that move from animals to humans (rabies, Creutzfeldt–Jakob disease) and those that are translocating from one part of the world to another (West Nile virus, cholera). The concluding section concerns novel treatment approaches, such as the use of immune globulin for streptococcal toxic shock and recent work on an AIDS vaccine.

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