To treat migraine symptoms after they develop, certain nonsteroidal anti-inflammatory drugs, such as ibuprofen and aspirin, are effective and safe. Good evidence supports the use of triptans (sumatriptan), but these drugs can cause serious side effects in people with heart disease, high blood pressure, or nerve weakness as a migraine symptom. While good evidence shows that dihydroergotamine nose spray works and is safe, evidence about other forms of ergotamines is unclear. There are very few studies of narcotics for migraine, and patients can become addicted to these agents. Anti-nausea drugs seem to work for patients who get nausea with migraines.