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Obesity in Adulthood and Its Consequences for Life Expectancy: A Life-Table Analysis

Anna Peeters, PhD; Jan J. Barendregt, PhD; Frans Willekens, PhD; Johan P. Mackenbach, MD, PhD; Abdullah Al Mamun, BSc(Hons), MSc; Luc Bonneux, MD, PhD, for NEDCOM, the Netherlands Epidemiology and Demography Compression of Morbidity Research Group*
[+] Article and Author Information

From Erasmus MC, Rotterdam, and University of Groningen, Groningen, the Netherlands.


Acknowledgments: The authors thank Caspar Looman, René Eijkemans, and Tommy Visscher for their contributions to the development of this study. The authors also thank the Framingham Heart Study coordinators for access to the original data set.

Grant Support: By grants from the Netherlands Heart Foundation (contract 98.138) and the Netherlands Organization for Scientific Research (contract 904-66-093), The Hague, the Netherlands.

Requests for Single Reprints: Anna Peeters, PhD, Department of Public Health, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, the Netherlands; e-mail, peeters@mgz.fgg.eur.nl.

Current Author Addresses: Drs. Peeters, Barendregt, Mackenbach, and Bonneux: Department of Public Health, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, the Netherlands.

Drs. Willekens and Al Mamun: Population Research Center, University of Groningen, PO Box 800, 9700 AV Groningen, the Netherlands.

Author Contributions: Conception and design: A. Peeters, J.P. Mackenbach, L. Bonneux.

Analysis and interpretation of the data: A. Peeters, J.J. Barendregt, J.P. Mackenbach, A. Al Mamun, L. Bonneux.

Drafting of the article: A. Peeters, L. Bonneux.

Critical revision of the article for important intellectual content: A. Peeters, J.J. Barendregt, J.P. Mackenbach, L. Bonneux.

Final approval of the article: A. Peeters, J.J. Barendregt, J.P. Mackenbach, L. Bonneux.

Provision of study materials or patients: A. Peeters.

Statistical expertise: J.J. Barendregt, F. Willekens, A. Al Mamun.

Obtaining of funding: J.J. Barendregt, J.P. Mackenbach, L. Bonneux.


Ann Intern Med. 2003;138(1):24-32. doi:10.7326/0003-4819-138-1-200301070-00008
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The characteristics at baseline within the Framingham Study cohort were generally as expected: The probability of death increased with each higher category of BMI group, the relationship between the prevalence of smoking and BMI group was inverse (Table 1), and age generally increased with each higher category of BMI group (78, 23). Although male nonsmokers were a small group and may represent an unusual cohort for that time, they were analyzed in the same way as the other groups. We did this because male nonsmokers had BMI-related risks similar to those of female nonsmokers and to findings in previous studies examining the relationship between BMI and mortality.

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Kaplan–Meier survival estimates for body mass index (BMI) groups I, II, and III within sex and smoking strata.
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Summary for Patients

Overweight and Obesity by Middle Age Are Associated with Shortened Lifespan

The summary below is from the full report titled “Obesity in Adulthood and Its Consequences for Life Expectancy: A Life-Table Analysis.” It is in the 7 January 2003 issue of Annals of Internal Medicine (volume 138, pages 24- 32). The authors are A Peeters, JJ Barendregt, F Willekens, JP Mackenbach, AAL Mamun, and L Bonneux, for the Netherlands Epidemiology and Demography Compression of Morbidity Research Group.

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