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Is a Strong Quadriceps Muscle Bad for a Patient with Knee Osteoarthritis?

Kenneth D. Brandt, MD
[+] Article, Author, and Disclosure Information

From Indiana University School of Medicine; Indianapolis, IN 46202.

Grant Support: In part by the National Institutes of Health (AR20582, ARA43348, AR44370).

Potential Financial Conflicts of Interest: None disclosed.

Requests for Single Reprints: Kenneth D. Brandt, MD, Indiana University School of Medicine, 1110 West Michigan Street, Room 545, Indianapolis, IN 46202; e-mail, kbrandt@iupui.edu.

Ann Intern Med. 2003;138(8):678-679. doi:10.7326/0003-4819-138-8-200304150-00017
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Awareness is increasing that nonpharmacologic measures are the keystone of management of patients with symptomatic knee osteoarthritis (12). Analgesics and nonsteroidal anti-inflammatory drugs augment the benefits of measures such as patient education about principles of joint protection; weight loss (if the patient is obese); and an exercise regimen that improves or maintains range of motion of the involved joint, strengthens periarticular muscles, and improves cardiovascular fitness. However, although a number of studies have described symptomatic benefit in patients with knee osteoarthritis following a variety of types of exercise (35), data on whether periarticular muscle strengthening affects the progression of structural damage have been unavailable.

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