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The Rate of Progression to Polycythemia Vera or Essential Thrombocythemia in Patients with Erythrocytosis or Thrombocytosis

Marco Ruggeri, MD; Alberto Tosetto, MD; Maurizio Frezzato, MD; and Francesco Rodeghiero, MD
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From S. Bortolo Hospital, Vicenza, Italy.

Acknowledgments: The authors thank the field investigators, secretaries, nurses, and laboratory technicians who worked with us. They especially thank the family doctors of the town of Vicenza for their enthusiastic collaboration.

Grant Support: By grants from Fondazione Cassa di Risparmio di Verona, Vicenza, Belluno, ed Ancona; ALT (Associazione per la Lotta alla Trombosi), Milan; and AVEC (Associazione Veneta per l'Emofilia e le Coagulopatie), Vicenza, Italy.

Potential Financial Conflicts of Interest: None disclosed.

Requests for Single Reprints: Francesco Rodeghiero, MD, Department of Hematology, S. Bortolo Hospital, 36100 Vicenza, Italy; e-mail, rodeghiero@hemato.ven.it

Current Author Addresses: Drs. Ruggeri, Tosetto, Frezzato, and Rodeghiero: Department of Hematology, S. Bortolo Hospital, via Rodolfi, 37, 36100 Vicenza, Italy.

Author Contributions: Conception and design: M. Ruggeri, A. Tosetto.

Analysis and interpretation of the data: M. Ruggeri, A. Tosetto.

Drafting of the article: M. Ruggeri, A. Tosetto, F. Rodeghiero.

Critical revision of the article for important intellectual content: M. Ruggeri, A. Tosetto, F. Rodeghiero.

Final approval of the article: M. Ruggeri, A. Tosetto, F. Rodeghiero.

Provision of study materials or patients: M. Frezzato.

Statistical expertise: A. Tosetto.

Obtaining of funding: F. Rodeghiero.

Administrative, technical, or logistic support: M. Frezzato.

Collection and assembly of the data: M. Frezzato.

Ann Intern Med. 2003;139(6):470-475. doi:10.7326/0003-4819-139-6-200309160-00009
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From June 1993 to September 1996, 13 780 eligible persons were contacted, and 10 059 were enrolled in the VITA project; the total accrual rate was 73%. The sample composition was almost identical to that of the original eligible sample. There were more women (53.4%) than men (46.6%) in the study group; the average age of men and women (43 years) was similar.

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Summary for Patients

Polycythemia Vera and Essential Thrombocythemia in a General Population

The summary below is from the full report titled “The Rate of Progression to Polycythemia Vera or Essential Thrombocythemia in Patients with Erythrocytosis or Thrombocytosis.” It is in the 16 September 2003 issue of Annals of Internal Medicine (volume 139, pages 470-475). The authors are M. Ruggeri, A. Tosetto, M. Frezzato, and F. Rodeghiero.


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