0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Using Risk for Advanced Proximal Colonic Neoplasia To Tailor Endoscopic Screening for Colorectal Cancer

Thomas F. Imperiale, MD; David R. Wagner, MS; Ching Y. Lin, BS; Gregory N. Larkin, MD; James D. Rogge, MD; and David F. Ransohoff, MD
[+] Article and Author Information

From Indiana University School of Medicine, Indiana University, Roudebush Veterans Affairs Medical Center, The Regenstrief Institute, Inc., Indianapolis Gastroenterology Research Foundation, and Eli Lilly and Co., Inc., Indianapolis, Indiana; and University of North Carolina, Chapel Hill, Chapel Hill, North Carolina.


Grant Support: In part by grant K24 DK 02756 from the National Institute of Diabetes and Digestive and Kidney Disorders (Dr. Imperiale).

Potential Financial Conflicts of Interest: At the time of data collection, Mr. Wagner was responsible for the Indianapolis Gastroenterology Research Foundation portion of the Eli Lilly colorectal cancer program, and a portion of his salary was paid by funds received from Lilly for program management.

Requests for Single Reprints: Thomas F. Imperiale, MD, The Regenstrief Institute, Inc., 1050 Wishard Boulevard, Indianapolis, IN 46202.

Current Author Addresses: Dr. Imperiale: The Regenstrief Institute, Inc., 1050 Wishard Boulevard, Indianapolis, IN 46202.

Ms. Lin: 6931 Middlebranch Avenue, Canton, OH 44721.

Dr. Rogge: Indianapolis Gastroenterology Research Foundation, 8051 South Emerson 200, Indianapolis, IN 46237.

Dr. Ransohoff: CB 7080, 4103 Bioinformatics Building, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7080.

Mr. Wagner: Med Institute, 1400 Cumberland Avenue, West Lafayette, IN 47906.

Dr. Larkin: Eli Lilly and Co., Lilly Corporate Center, DC 2111, Indianapolis, IN 46285.

Author Contributions: Conception and design: T.F. Imperiale, D.R. Wagner, D.F. Ransohoff.

Analysis and interpretation of the data: T.F. Imperiale, D.R. Wagner, C.Y. Lin, D.F. Ransohoff.

Drafting of the article: T.F. Imperiale, D.F. Ransohoff.

Critical revision of the article for important intellectual content: T.F. Imperiale, D.R. Wagner, G.N. Larkin, J.D. Rogge, D.F. Ransohoff.

Final approval of the article: T.F. Imperiale, J.D. Rogge, D.F. Ransohoff.

Provision of study materials or patients: D.R. Wagner, G.N. Larkin, J.D. Rogge.

Statistical expertise: T.F. Imperiale.

Obtaining of funding: T.F. Imperiale.

Administrative, technical, or logistic support: D.R. Wagner, C.Y. Lin, G.N. Larkin.

Collection and assembly of data: T.F. Imperiale, D.R. Wagner, C.Y. Lin.


Ann Intern Med. 2003;139(12):959-965. doi:10.7326/0003-4819-139-12-200312160-00005
Text Size: A A A

The finding that sigmoidoscopy alone may fail to detect between 40% and 50% of advanced proximal neoplasms has led to calls for universal colonoscopy (12). However, the feasibility of this strategy may be limited by cost; safety; resource constraints; and an uncertain incremental benefit of colonoscopy on meaningful patient outcomes, such as mortality and quality of life (9). Although periodic sigmoidoscopy is recommended as an acceptable and equally preferred option among several tests, it is unclear in which patients sigmoidoscopy alone may be considered especially suitable. Some investigators have suggested that the intensity of testing be tailored to a person's risk (2326), but tailoring cannot effectively be done without detailed information about risk.

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Using Risks To Tailor Screening for Colorectal Cancer

The summary below is from the full report titled “Using Risk for Advanced Proximal Colonic Neoplasia To Tailor Endoscopic Screening for Colorectal Cancer.” It is in the 16 December 2003 issue of Annals of Internal Medicine (volume 139, pages 959-965). The authors are T.F. Imperiale, D.R. Wagner, C.Y. Lin, G.N. Larkin, J.D. Rogge, and D.F. Ransohoff.

Read More...

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)