Table 1 shows quartile estimates of survival for patients with Alzheimer disease according to baseline characteristics. Median survival was longer for younger persons and women but did not vary by education level. Patients age 85 years and older, with gait disturbance, wandering, and comorbid diabetes and congestive heart failure had the poorest survival (median survival times were 3.2 years, 3.5 years, 4.1 years, 3.8 years, and 3.0 years, respectively; P< 0.01 for all comparisons [log-rank test]). Other predictors of decreased survival were male sex, lower MMSE score, higher (worse) DRS score, presence of frontal release signs, presence of extrapyramidal signs, history of falls, presence of urinary incontinence, history of ischemic heart disease, and history of stroke. Duration of survival among patients with Alzheimer disease did not differ by ethnicity, presence of hypertension, presence of psychiatric symptoms, presence of behavioral disturbances, presence of depression symptoms, or duration of dementia symptoms at the time of diagnosis.