All retirees lost weight. Compared with those taking placebos, retirees treated with drugs had a 20% decrease in total cholesterol level, 26% decrease in LDL cholesterol level, 50% decrease in triglyceride level, and 36% increase in HDL cholesterol level. Coronary lesions regressed with drug therapy and progressed without drug therapy. Retirees receiving drug therapy had fewer total cardiovascular events, such as hospitalizations for chest pain and bypass procedures, than did those taking placebos. They also had more flushing, skin rashes, and abdominal pain.