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Responding to the Rofecoxib Withdrawal Crisis: A New Model for Notifying Patients at Risk and Their Health Care Providers

Anil Jain, MD; Ashish Atreja, MD, MPH; C. Martin Harris, MD, MBA; Meghan Lehmann, PharmD; Jon Burns, BS; and James Young, MD
[+] Article and Author Information

From The Cleveland Clinic Foundation, Cleveland, Ohio.


Potential Financial Conflicts of Interest: Consultancies: J. Young (Merck & Co., Inc.; AstraZeneca; Pfizer, Inc.); Grants received: J. Young (Merck & Co., Inc.; AstraZeneca; Pfizer, Inc.).

Requests for Single Reprints: Anil Jain, MD, Cleveland Clinic Foundation, A91, 9500 Euclid Avenue, Cleveland, OH 44195.

Current Author Addresses: Drs. Jain and Atreja: Cleveland Clinic Foundation, A91, 9500 Euclid Avenue, Cleveland, OH 44195.

Dr. Lehmann: Department of Pharmacy/Hb03, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195.

Dr. Young: Cleveland Clinic Foundation, T13, 9500 Euclid Avenue, Cleveland, OH 44195.

Mr. Burns: Cleveland Clinic Foundation, CL30, 9500 Euclid Avenue, Cleveland, OH 44195.

Dr. Harris: Cleveland Clinic Foundation, H18, 9500 Euclid Avenue, Cleveland, OH 44195.


Ann Intern Med. 2005;142(3):182-186. doi:10.7326/0003-4819-142-3-200502010-00008
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With the health care environment becoming more complex and specialized, the utility of EMR technology to facilitate communication about important health care issues is critical. This report describes an immediate response to a major drug withdrawal using EMR patient data in combination with readily available, automated communication tools. We identified and notified 11 699 patients receiving rofecoxib who were actively managed in our EMR. We also identified 842 prescribing providers within a short time after the FDA Public Health Advisory and provided them a list of their patients.

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