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Cardiac Resynchronization Therapy in Heart Failure

Melanie Calvert, PhD; Nick Freemantle, PhD; and John G.F. Cleland, MD
[+] Article, Author, and Disclosure Information

From University of Birmingham Medical School, Edgbaston B15 2TT, and University of Hull, Kingston upon Hull HU16 5JQ, England, United Kingdom.

Note: Drs. Freemantle and Cleland are steering committee members for the CArdiac REsynchronisation in Heart Failure (CARE-HF) trial. Drs. Freemantle and Calvert are responsible for the analysis of the CARE-HF trial.

Ann Intern Med. 2005;142(4):305-307. doi:10.7326/0003-4819-142-4-200502150-00017
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Unconfounded all-cause mortality with cardiac resynchronization therapy (CRT) versus randomly assigned controls.

CHF = congestive heart failure; COMPANION = Comparison of Medical Therapy, Pacing, and Defibrillation in Chronic Heart Failure; CONTAK-CD = Guidant CONTAK CD CRT-D System Trial; MIRACLE = Multicenter InSync Randomized Clinical Evaluation; MIRACLE-ICD = Multicenter InSync Randomized Clinical Evaluation ICD [implantable cardioverter defibrillator]; MUSTIC-AF = Multisite Stimulation in Cardiomyopathies Atrial Fibrillation; MUSTIC-SR = Multisite Stimulation in Cardiomyopathies Sinus Rhythm; PATH-CHF = Pacing Therapies for Congestive Heart Failure.

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