Chronic kidney disease is a gradual and progressive loss of function in both kidneys. Many patients with chronic kidney disease have high blood pressure. Doctors usually use drugs to reduce blood pressure and decrease risks for heart attacks, strokes, and kidney failure. Most experts recommend reducing blood pressure to less than 140/90 mm Hg in adults with high blood pressure. In adults with certain conditions, such as diabetes or chronic kidney disease, experts often recommend reducing blood pressure to less than 130/80 mm Hg. No long-term clinical trials have tested whether reducing blood pressure to the lower levels prevents kidney failure in patients with chronic kidney disease.