The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

The Middle-Aged and Older American: Wrong Prototype for a Preventive Polypill?

Cynthia Mulrow, MD, MSc, Deputy Editor; and William Kussmaul, MD, Associate Editor
[+] Article, Author, and Disclosure Information

Potential Financial Conflicts of Interest: None disclosed.

Requests for Single Reprints: Customer Service, American College of Physicians, 190 N. Independence Mall West, Philadelphia, PA 19106.

Current Author Addresses: Dr. Mulrow: American College of Physicians, 190 N. Independence Mall West, Philadelphia, PA 19106-1572.

Dr. Kussmaul: Hahnemann University Hospital, 227 North Broad Street, Suite 200, Philadelphia, PA 19107.

Ann Intern Med. 2005;142(6):467-468. doi:10.7326/0003-4819-142-6-200503150-00012
Text Size: A A A

Any way you look at them, the numbers are staggering. In the coming year, about 1.2 million Americans will have a first or recurrent coronary attack and about 700 000 will have a new or recurrent stroke (1). Most Americans older than age 35 years have 1 or more vascular risk factors. More than one third of them have hypercholesterolemia (2). One fifth of adult Americans smoke, and most have inactive lifestyles (3). One third have high blood pressure, more than 30% are obese, and nearly 10% have diabetes (4).

First Page Preview

View Large
First page PDF preview





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $32.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.