Wegener granulomatosis is an uncommon disease in which the blood vessels are inflamed (vasculitis). The inflammation of the vessels limits blood flow to body organs. Wegener granulomatosis mainly affects the respiratory tract and the kidneys. Symptoms are often vague and may include cold symptoms, such as runny nose, sinus pain, bloody discharge from the nose, cough, shortness of breath, joint pains, rashes, weakness, or tiredness. Some patients with Wegener granulomatosis also get blood clots in their veins (venous thromboembolism or VTE). These clots can cause serious and even fatal complications. Researchers do not know how often VTEs occur in patients with Wegener granulomatosis.