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Diet and Cholesterol Reduction

David J.A. Jenkins, MD, PhD, DSc; Cyril W.C. Kendall, PhD; and Augustine Marchie, MSc
[+] Article, Author, and Disclosure Information

From St. Michael's Hospital and University of Toronto; Toronto, Ontario M5C 2T2, Canada

Potential Financial Conflicts of Interest: Consultancies: D.J.A. Jenkins (Solae, Almond Board of California); Honoraria: D.J.A. Jenkins (Oldways Preservation and Exchange Trust, Almond Board of California, Dried Plum Board of California), C.W.C. Kendall (Almond Board of California, Loblaw Brands Ltd., Unilever); Stock ownership or options (other than mutual funds): D.J.A. Jenkins (Pacific Health Laboratories, Inc.); Grants received: D.J.A. Jenkins and C.W.C. Kendall (Barilla, Solae, Unilever, Hain Celestial Group, Loblaw Brands Ltd., Sanitarium Co., Almond Board of California, International Tree Nut Council); Other: D.J.A. Jenkins (Loblaw Brands Ltd., Sanitarium Co., Herbalife International, Nutritional Fundamentals for Health, Pacific Health Laboratories, Inc., California Strawberry Commission, Metagenics).

Requests for Single Reprints: David J.A. Jenkins, MD, PhD, DSc, Clinical Nutrition and Risk Factor Modification Center, St. Michael's Hospital, 61 Queen Street East, Toronto, Ontario M5C 2T2, Canada; e-mail, mailto:cyril.kendall@utoronto.ca.

Current Author Addresses: Dr. Jenkins: Clinical Nutrition and Risk Factor Modification Center, St. Michael's Hospital, 61 Queen Street East, Toronto, Ontario M5C 2T2, Canada.

Dr. Kendall and Mr. Marchie: Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 3E2, Canada.

Ann Intern Med. 2005;142(9):793-795. doi:10.7326/0003-4819-142-9-200505030-00017
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After a comprehensive assessment of recent clinical evidence, the most current National Cholesterol Education Program Adult Treatment Panel (ATP) III guidelines call for renewed emphasis on lowering levels of serum cholesterol (1). The ATP III update recommends that physicians set a low-density lipoprotein (LDL) cholesterol goal of less than 1.8 mmol/L (<70 mg/dL) for high-risk patients, based on studies such as the Heart Protection Study (2). Although the cut-points of 3.4 mmol/L (130 mg/dL) and 4.1 mmol/L (160 mg/dL) for LDL cholesterol in moderate- and low-risk individuals remain unaltered, it may not be long before they are also lowered.


cholesterol ; diet

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