Doctors commonly insert long thin plastic tubes (catheters) into the veins of critically ill patients to deliver fluids and medicines and also to measure pressures inside blood vessels near the heart. This type of catheter (central venous catheter) is inserted into a large vein in the neck (jugular vein) or under the collarbone (subclavian). Although central venous catheters can be very useful, they also have a significant risk for becoming contaminated (colonized) with bacteria, which may then spread to the bloodstream. One potentially useful approach to preventing bacterial colonization and spread is using a catheter that has been coated with an antiseptic. A new catheter, which is coated on both its outer surface and its inner surface, has recently been developed.