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Tumor Necrosis Factor-α Inhibitor Therapy in Erosive Polyarthritis Secondary to Systemic Sclerosis

Silvia Bosello, MD; Maria De Santis, MD; Barbara Tolusso, BS; Angelo Zoli, MD; and Gianfranco Ferraccioli, MD
[+] Article, Author, and Disclosure Information

From the Catholic University of the Sacred Heart, 00168 Rome, Italy.

Potential Financial Conflicts of Interest: None disclosed.

Ann Intern Med. 2005;143(12):918-920. doi:10.7326/0003-4819-143-12-200512200-00019
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Grahic Jump Location
Major clinical features in 2 patients.

Panel A shows patient 2's fixation of prossimal and distal interphalangeal joints at baseline. After 6 months, the patient's joints reached a range of motion of 30 degrees to 60 degrees (B); range of motion in the metacarpophalangeal joints also increased. Panel C shows necrotic fingertip ulceration present at baseline in patient 3. After the second infusion of infliximab, the ulcer improved substantially (D).

Grahic Jump Location




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