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Hepatitis C: A Bitter Harvest

Jules L. Dienstag, MD
[+] Article, Author, and Disclosure Information

From Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114.

Potential Financial Conflicts of Interest: Other: GlaxoSmithKline, Vertex, Bristol-Myers Squibb, Gilead Sciences, Idenix Pharmaceuticals, Achillion Pharmaceuticals, Metabasis Therapeutics, SciClone, Nucleonics, Valeant, Schering-Plough Research Institute; Consultancies: Oxxon Therapeutics, CombinatoRx, Pharmasset.

Requests for Single Reprints: Jules L. Dienstag, MD, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114; e-mail, jdienstag@partners.org.

Ann Intern Med. 2006;144(10):770-771. doi:10.7326/0003-4819-144-10-200605160-00011
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We know a lot about chronic infection with hepatitis C virus (HCV): It affects 170 million people worldwide, accounts for approximately 40% of all cases of chronic liver disease, can be associated with hepatic decompensation and hepatocellular carcinoma, and is the most common indication for liver transplantation (1). Although we have learned so much about this disease during the past 3 decades, we continue to be surprised by new insights and revelations.


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