Currently, doctors evaluate a patient's chances of developing cardiovascular disease by examining risk factors, such as cholesterol levels, diabetes, high blood pressure, smoking status, and age. Sometimes doctors use mathematical models to estimate the chance that a person will develop cardiovascular disease in the future. The Framingham risk model is a model that doctors commonly use. The model is useful, but not perfect. Some people who have no risk factors develop cardiovascular disease. Others who have multiple risk factors don't develop disease. Researchers wonder whether adding additional factors, such as CRP, to the Framingham model would improve the ability to estimate a person's chances of developing disease.