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Update in Rheumatology

David B. Hellmann, MD; and John B. Imboden, MD
[+] Article, Author, and Disclosure Information

From Johns Hopkins University, Baltimore, Maryland, and University of California San Francisco, San Francisco, California.

Grant Support: In part by the Rosalind Russell Arthritis Research Center.

Potential Financial Conflicts of Interest: None disclosed.

Requests for Single Reprints: David B. Hellmann, MD, Department of Medicine, Room 109, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, B-1-North, Baltimore, MD 21224; e-mail, hellmann@jhmi.edu.

Current Author Addresses: Dr. Hellmann: Department of Medicine, Room 109, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, B-1-North, Baltimore, MD 21224.

Dr. Imboden: Department of Medicine, University of California, San Francisco, Box 0868, San Francisco, CA 94143.

Ann Intern Med. 2006;145(11):834-838. doi:10.7326/0003-4819-145-11-200612050-00008
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This year's Update in Rheumatology includes discussions of advances related to rheumatoid arthritis, systemic lupus erythematosus, Wegener granulomatosis, antineutrophil cytoplasmic antibody–associated vasculitis, and gout. Changes to clinical practice emerging from these articles are shown in the Table.

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Too many drugs
Posted on December 6, 2006
milind m deshpande
Vivekanand Hospital,Hubli,Karnataka,India.
Conflict of Interest: None Declared

Sir No doubt,a combination therapy straight away for the early rheumatoids ends up in a better functional result but imagine treating a case of RA with diabetes,hypertension,hypercholesterolemia and osteoporosis on metformin,glimeperide,atenolol,amlodipine,atorvastatin,calcium,methylcobalamin and we contemplate a combination therapy for RA!Too many drugs and too many interactions and poor compliance and the adverse drug events!!More the associated problems more should be the role of monotherapy and then step up if required.

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