The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

The BeSt Way to Treat Early Rheumatoid Arthritis?

James R. O'Dell, MD
[+] Article, Author, and Disclosure Information

From University of Nebraska Medical Center, Omaha, NE 68198.

Potential Financial Conflicts of Interest: None disclosed.

Requests for Single Reprints: James R. O'Dell, MD, Department of Internal Medicine, University of Nebraska Medical Center, 983025 Nebraska Medical Center, Omaha, NE 68198-3025.

Ann Intern Med. 2007;146(6):459-460. doi:10.7326/0003-4819-146-6-200703200-00014
Text Size: A A A

Over the past few years, the outlook for patients who are newly diagnosed with rheumatoid arthritis (RA) has improved dramatically (1) because of several key advances, including early use of disease-modifying, antirheumatic drugs (DMARDs); the use of DMARDs in combination; use of biologicals, especially antitumor necrosis factor-α agents; and recognition of the critical role of inflammation in the vascular complications that lead directly to death. Patients who are diagnosed with RA today are much less likely to become disabled, require joint replacement (2), or die of premature atherosclerotic disease, which is associated with RA-related systemic inflammation.

First Page Preview

View Large
First page PDF preview





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $32.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.