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Optimal Treatment of Chronic Obstructive Pulmonary Disease: The Search for the Magic Combination of Inhaled Bronchodilators and Corticosteroids

Gerard J. Criner, MD
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From Temple University School of Medicine, Philadelphia, Pennsylvania.

Potential Financial Conflicts of Interest: Consultancies: Ortho Biotech, Schering-Plough, Boehringer Ingelheim, Actelion, Shire Pharmaceuticals, Sepracor Pharmaceuticals; Honoraria: Ortho Biotech, Schering-Plough, Boehringer Ingelheim, Actelion, Shire Pharmaceuticals, Sepracor Pharmaceuticals; Grants received: Schering-Plough, Boehringer Ingelheim, Actelion, GlaxoSmithKline, Altana Pharma, Daiichi Asubio Pharmaceuticals, Pfizer Inc., Roche Pharmaceuticals, Sepracor Pharmaceuticals, Emphasys Medical Inc., Aeris Therapeutics Inc.; Grants pending: Boehringer Ingelheim, GlaxoSmithKline.

Requests for Single Reprints: Gerard J. Criner, MD, Pulmonary and Critical Care Medicine and Temple Lung Center, Temple University School of Medicine, 745 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140; e-mail, crinerg@tuhs.temple.edu.

Ann Intern Med. 2007;146(8):606-608. doi:10.7326/0003-4819-146-8-200704170-00012
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Chronic obstructive pulmonary disease (COPD) is an international disease: Not only does it affect 10 to 24 million adults in the United States (1), but it is also the fourth leading cause of death in both the United States and the world (2). The global burden of COPD will increase dramatically in the coming years (3). A recent assessment by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) projects that COPD will be the fifth leading cause of disease worldwide and the third leading cause of death by 2020 (3).

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