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Sirolimus Treatment for Pulmonary Lymphangioleiomyomatosis

Camille Taillé, MD, PhD; Marie-Pierre Debray, MD; and Bruno Crestani, PhD
[+] Article, Author, and Disclosure Information

From Hôpital Bichat–Claude Bernard and Hôpitaux de Paris, Paris 75018, France.

Potential Financial Conflicts of Interest: None disclosed.

Ann Intern Med. 2007;146(9):687-688. doi:10.7326/0003-4819-146-9-200705010-00022
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Magnetic resonance imaging and computed tomography scans.

A. Right chylothorax was observed at diagnosis. B. The chylothorax completely disappeared after 3 months of sirolimus treatment. C. Axial fast spin-echo T2-weighted magnetic resonance imaging scan of the pelvis revealed large retroperitoneal and pelvic masses (arrows) at diagnosis. D. After 8 months of treatment, no abdominal mass was observed (arrows). Magnetic resonance imaging was always done at the same hour to avoid diurnal variation of lymphangioleimomyoma size.

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