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Treatment of Familial Mediterranean Fever with Anakinra

Rakiba Belkhir, MD; Luc Moulonguet-Doleris, MD; Eric Hachulla, MD, PhD; Jacques Prinseau, MD; Alain Baglin, MD; and Thomas Hanslik, MD, PhD
[+] Article, Author, and Disclosure Information

From Hôpital Ambroise Paré, Boulogne 92104, France.

Potential Financial Conflicts of Interest: None disclosed.

Ann Intern Med. 2007;146(11):825-826. doi:10.7326/0003-4819-146-11-200706050-00023
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Grahic Jump Location
Figure. The patient was receiving colchicine, 1 mg/d, until 9 June 2005, when the dosage was increased to 1.5 mg/d through 8 November 2005, when the treatment was stopped. From 29 November 2005, colchicine treatment was introduced again at a dosage of 0.5 mg/d. Anakinra treatment, 100 mg every other day, was started at the same time, was increased to 100 mg/d between 28 December 2005 and 21 April 2006 and from July 2006. From 21 April to July 2006, the patient did not receive anakinra. *Anakinra treatment started. †Anakinra treatment stopped. ‡Anakinra treatment restarted.
C-reactive protein (CRP) and serum amyloid A (SAA) values at baseline and their improvement during anakinra treatment.
Grahic Jump Location




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