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Ethical Considerations of Comparing Sequential and Traditional Anti–Helicobacter pylori Therapy

David Y. Graham, MD; and Yoshio Yamaoka, MD, PhD
[+] Article, Author, and Disclosure Information

From Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030.

Potential Financial Conflicts of Interest: Dr. Graham has received small amounts of grant support and/or free drugs or urea breath tests from Meretek Diagnostics, Janssen/Eisai, TAP Pharmaceuticals, and Biohit for investigator-initiated and investigator-controlled research in the area of H. pylori infection. He is a paid consultant for Otsuka Pharmaceuticals; a member of the Board of Directors of Meretek Diagnostics, the manufacturer of the 13C-urea breath test; and a consultant to Novartis with regard to H. pylori vaccine development. Finally, he receives royalties on the Baylor College of Medicine patent covering the serologic test HM-CAP (E-Z-EM, Lake Success, New York).

Ann Intern Med. 2007;147(6):434-435. doi:10.7326/0003-4819-147-6-200709180-00022
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Grahic Jump Location
Figure 1.
Results of the 5 previous comparisons of legacy triple and sequential therapy.P

Each bar shows mean and upper 95% CI values. All comparisons between sequential and triple therapy were significant (  < 0.05).

Grahic Jump Location




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